Unlock a rare development opportunity in the heart of Potrero Hill with this vacant duplex at 2109-2111 22nd Street. Perfectly positioned in one of San Francisco’s most coveted neighborhoods, this property features two charming "mini-residences" offering immediate versatility: a light-filled top-floor unit with a private deck and a lower-level retreat leading to an expansive patio. Situated on a deep lot, the site serves as a blank canvas for a visionary expansion or a lush urban garden sanctuary. The location is a commuter’s dream with seamless freeway access and close proximity to Zuckerberg San Francisco General, UCSF Mission Bay, and the convenience of Whole Foods just blocks away. Add this duplex to your portfolio and take advantage of city’s current red hot rental market, or develop the property to maximize its potential in one of San Francisco’s coolest neighborhoods Potrero Hill.
Listing courtesy of Herman Chan from Golden Gate Sotheby's Int'l Re. 415-787-3450

Bay East © 2026. CCAR © 2026. BridgeMLS © 2026. Information Deemed Reliable But Not Guaranteed. This information is being provided by the Bay East MLS, or CCAR MLS, or bridgeMLS. The listings presented here may or may not be listed by the Broker/Agent operating this website. This information is intended for the personal use of consumers and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Data last updated on: